{"id":4451,"date":"2022-07-22T10:00:53","date_gmt":"2022-07-22T08:00:53","guid":{"rendered":"https:\/\/www.taam.cnrs.fr\/?page_id=4451"},"modified":"2022-07-22T10:07:23","modified_gmt":"2022-07-22T08:07:23","slug":"animal-research-good-practice","status":"publish","type":"page","link":"https:\/\/www.taam.cnrs.fr\/index.php\/animal-research-good-practice\/?lang=en","title":{"rendered":"Animal research &#8211; Good practice"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"4451\" class=\"elementor elementor-4451 elementor-159\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-87d0ac8 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"87d0ac8\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-4dc18f49\" data-id=\"4dc18f49\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4a8b1dec elementor-widget elementor-widget-text-editor\" data-id=\"4a8b1dec\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><\/p><p>For all daily procedures, from changing cages to surgical operations, the PHENOMIN teams respect good veterinary practices. Our permanent staff receives continuous training to maintain high level skills and new recruits are trained by means of a tutoring system. We also use various tools which are available on the web:<\/p><p><\/p><ul class=\"wp-block-list\"><li><a href=\"http:\/\/www.procedureswithcare.org.uk\/administration-of-substances\/\" target=\"_blank\" rel=\"noreferrer noopener\">http:\/\/www.procedureswithcare.org.uk\/administration-of-substances\/<\/a><\/li><li><a href=\"http:\/\/research.utsa.edu\/research-funding\/laboratory-animal-resources-center\/training\/\" target=\"_blank\" rel=\"noreferrer noopener\">http:\/\/research.utsa.edu\/research-funding\/laboratory-animal-resources-center\/training\/<\/a><\/li><li><a href=\"https:\/\/norecopa.no\/films-and-slide-shows\/mouse\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/norecopa.no\/films-and-slide-shows\/mouse<\/a><\/li><li><a href=\"https:\/\/www.nc3rs.org.uk\/mouse-handling-tutorial\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.nc3rs.org.uk\/mouse-handling-tutorial<\/a><\/li><\/ul><p><\/p><p><strong>Harmful phenotypes and welfare assessment<\/strong><\/p><p><\/p><p>PHENOMIN creates lines of genetically modified mice and rats in its platforms. In this context, we have developed standardised tools to assess the phenotypes of lines which have been newly created in our housing conditions. Our animals travel with their welfare assessment when they are transferred between PHENOMIN institutes or when they are distributed over the world.<\/p><p><\/p><p>The tools used by the PHENOMIN teams have been designed according to the recommendations laid down by the Working Group of European Experts on assessment of severity.<\/p><p><\/p><p>Welfare is assessed at different ages, in particular at early stages, in order to evaluate all neonatal mortality (<a href=\"https:\/\/www.nc3rs.org.uk\/it-starts-very-beginning-importance-neonate-assessment\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.nc3rs.org.uk\/it-starts-very-beginning-importance-neonate-assessment<\/a>, and during the ageing process, since age has a huge impact on animal studies (<a href=\"https:\/\/www.nc3rs.org.uk\/impact-rodent-age-study-outcome\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.nc3rs.org.uk\/impact-rodent-age-study-outcome<\/a>).<\/p><p><\/p><p><strong>Pain measurement<\/strong><\/p><p><\/p><p>In order to respect the animals\u2019 welfare and to avoid any unnecessary pain and suffering, the PHENOMIN teams use scoring systems to monitor ethical boundary points.<\/p><p><\/p><p>For example, PHENOMIN and its ethics committee have developed a scoring sheet for pain based on various criteria such as appearance and behaviour (body score assessment : <a href=\"https:\/\/www.researchgate.net\/publication\/229438758\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.researchgate.net\/publication\/229438758<\/a>).<\/p><p><\/p><p>The Mouse Grimace Scale is also widely used in our installations to provide a quick check on the animals\u2019 health.<\/p><p><\/p><p><strong>Continuous training, e-learning, specific training courses<\/strong><\/p><p><\/p><p>PHENOMIN proposes various specific training courses to help research teams acquire new skills: breeding, imaging, phenotyping\u2026. as is done regularly on PHENOMIN sites.<\/p><p><\/p><p><strong>Useful links<\/strong><\/p><p><\/p><ul class=\"wp-block-list\"><li><a href=\"http:\/\/www.ccac.ca\/\" target=\"_blank\" rel=\"noopener\">Canadian Council on Animal Care<\/a><\/li><li><a href=\"http:\/\/www.recherche-animale.org\/\" target=\"_blank\" rel=\"noopener\">Recherche animale (ex-GIRCOR)<\/a>\u00a0and\u00a0<a href=\"http:\/\/us4.campaign-archive2.com\/?u=078873b339223aa97581ba835&amp;id=329ef717d4&amp;e=772c5a42b8\">i<\/a><a href=\"http:\/\/us4.campaign-archive2.com\/?u=078873b339223aa97581ba835&amp;id=329ef717d4&amp;e=772c5a42b8\" target=\"_blank\" rel=\"noopener\">ts news letter<\/a><\/li><li><a href=\"http:\/\/register.consilium.europa.eu\/pdf\/en\/10\/st06\/st06106.en10.pdf\" target=\"_blank\" rel=\"noopener\">European Directive on the Protection of Animals used on Scientific Purpose<\/a><\/li><li><a href=\"http:\/\/www.fbresearch.org\/\" target=\"_blank\" rel=\"noopener\">Foundation for Biomedical Research<\/a><\/li><li><a href=\"http:\/\/www.basel-declaration.org\/basel-declaration\/download-the-declaration\/\" target=\"_blank\" rel=\"noopener\">Basel declaration<\/a><\/li><li><a href=\"https:\/\/www.nc3rs.org.uk\/\" target=\"_blank\" rel=\"noopener\">NC3R<\/a><\/li><li><a href=\"http:\/\/www.understandinganimalresearch.org.uk\/\" target=\"_blank\" rel=\"noopener\">http:\/\/www.understandinganimalresearch.org.uk\/<\/a><\/li><li><a href=\"http:\/\/www.crackit.org.uk\" target=\"_blank\" rel=\"noopener\">http:\/\/www.crackit.org.uk<\/a><\/li><\/ul><p><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>For all daily procedures, from changing cages to surgical operations, the PHENOMIN teams respect good veterinary practices. Our permanent staff receives continuous training to maintain high level skills and new recruits are trained by means of a tutoring system. We also use various tools which are available on the web: http:\/\/www.procedureswithcare.org.uk\/administration-of-substances\/ http:\/\/research.utsa.edu\/research-funding\/laboratory-animal-resources-center\/training\/ https:\/\/norecopa.no\/films-and-slide-shows\/mouse https:\/\/www.nc3rs.org.uk\/mouse-handling-tutorial Harmful&hellip; <br \/> <a class=\"read-more\" href=\"https:\/\/www.taam.cnrs.fr\/index.php\/animal-research-good-practice\/?lang=en\">Read more<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-4451","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Animal research - Good practice - TAAM - CNRS Orl\u00e9ans<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.taam.cnrs.fr\/index.php\/en\/animal-research-good-practice\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Animal research - Good practice - TAAM - CNRS Orl\u00e9ans\" \/>\n<meta property=\"og:description\" content=\"For all daily procedures, from changing cages to surgical operations, the PHENOMIN teams respect good veterinary practices. Our permanent staff receives continuous training to maintain high level skills and new recruits are trained by means of a tutoring system. 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